Medicine

Advancing ASO treatments from growth to application

.Contending rate of interests.R.S., M.S., H.G. and also A.A.R. are actually planners of the 1M1M project. H.G. and A.A.R. are actually board of supervisors participants and R.S., M.S. as well as A.A.R. are actually participants of the medical consultatory board of N1C. A.A.R. makes known employment through LUMC, which possesses licenses on exon-skipping innovation, a number of which has been actually licensed to BioMarin and also ultimately sublicensed to Sarepta. As co-inventor of a few of these patents, A.A.R. was actually qualified to a share of royalties. A.A.R. even more reveals working as ad hoc expert for PTC Rehabs, Sarepta Therapies, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco as well as Astra Zeneca. Before 5 years, A.A.R. also performed ad hoc seeking advice from for Alpha Anomeric. A.A.R. also discloses membership of the scientific advisory boards of Eisai, Hybridize Therapeutics, Muteness Therapeutics, Sarepta Therapies, Sapreme and Mitorx. Before 5 years, A.A.R. was actually likewise a scientific board of advisers member for ProQR. Commission for A.A.R. u00e2 s consulting and also advising activities is paid to LUMC. Before 5 years, LUMC likewise received speaker gratuity coming from PTC Rehabs, Alnylam Netherlands, Italfarmaco and also Pfizer and also moneying for agreement research study from Sapreme, Eisai, Galapagos, Synaffix and Alpha Anomeric. Venture financing is actually acquired from Sarepta Rehabs and Entrada through unrestricted grants. H.G. possesses absolutely nothing to disclose relative to the subjects covered in this particular composition. Before 5 years, he has actually also gotten working as a consultant gratuity coming from UCB. M.S. got consultancy gratuity coming from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and Solaxa in the past 5 years, all irrelevant to the present composition. R.S. has nothing to divulge relative to the subject matters dealt with within this document. She has gotten sound speaker and/or consultancy gratuity or even sponsoring contributions from Abbvie, Bial, STADA as well as Everpharma previously 5 years.